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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY2
All Species:
10.91
Human Site:
S681
Identified Species:
18.46
UniProt:
Q9Y3R5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R5
NP_005119.2
2298
258184
S681
N
D
S
S
R
K
N
S
W
E
P
K
P
I
T
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
S681
N
D
S
S
R
K
N
S
W
E
P
K
P
I
T
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
S669
E
D
C
S
R
K
N
S
W
E
P
K
P
I
T
Dog
Lupus familis
XP_544874
2297
257913
P681
S
D
S
D
R
K
N
P
W
D
A
K
P
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHQ6
2295
257491
D681
P
G
R
K
S
S
W
D
P
K
P
I
T
V
P
Rat
Rattus norvegicus
XP_001055500
2294
257490
E680
S
G
R
K
S
S
W
E
P
K
P
I
T
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512569
2247
251024
W681
S
A
K
K
R
S
S
W
E
A
K
A
I
T
V
Chicken
Gallus gallus
XP_001232723
2283
257889
I679
E
S
A
S
K
K
K
I
A
K
Q
I
T
V
P
Frog
Xenopus laevis
Q642P2
2270
256829
I677
G
S
W
Q
P
K
Q
I
T
G
P
Q
F
K
Q
Zebra Danio
Brachydanio rerio
NP_956904
817
86774
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
A704
Q
L
D
E
E
S
R
A
T
Q
Q
R
G
F
S
Honey Bee
Apis mellifera
XP_395999
2434
273219
T668
K
N
S
I
M
G
S
T
G
S
L
G
R
G
P
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
T758
D
D
F
Y
D
E
M
T
H
V
L
L
K
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03921
1698
194669
I168
I
S
S
L
L
P
G
I
D
D
E
S
N
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
89.9
N.A.
86.4
86.4
N.A.
73.9
75.2
69
21.9
N.A.
27.6
32.1
22.3
N.A.
Protein Similarity:
100
99.7
96
94.6
N.A.
92.4
92.5
N.A.
83
85.4
82
28.7
N.A.
47
53.2
40.9
N.A.
P-Site Identity:
100
100
86.6
60
N.A.
6.6
6.6
N.A.
6.6
13.3
13.3
0
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
86.6
80
N.A.
20
26.6
N.A.
20
40
20
0
N.A.
26.6
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
8
8
8
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
36
8
8
8
0
0
8
8
15
0
0
0
8
0
% D
% Glu:
15
0
0
8
8
8
0
8
8
22
8
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
8
% F
% Gly:
8
15
0
0
0
8
8
0
8
8
0
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
22
0
0
0
22
8
29
0
% I
% Lys:
8
0
8
22
8
43
8
0
0
22
8
29
8
8
0
% K
% Leu:
0
8
0
8
8
0
0
0
0
0
15
8
0
0
8
% L
% Met:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
15
8
0
0
0
0
29
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
0
8
8
0
8
15
0
43
0
29
8
29
% P
% Gln:
8
0
0
8
0
0
8
0
0
8
15
8
0
0
8
% Q
% Arg:
0
0
15
0
36
0
8
0
0
0
0
8
8
0
0
% R
% Ser:
22
22
36
29
15
29
15
22
0
8
0
8
0
0
15
% S
% Thr:
0
0
0
0
0
0
0
15
15
0
0
0
22
8
22
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
22
8
% V
% Trp:
0
0
8
0
0
0
15
8
29
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _